Liprin-α1 modulates cancer cell signaling by transmembrane protein CD82 in adhesive membrane domains linked to cytoskeleton
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چکیده
منابع مشابه
Liprin-α1 is a regulator of vimentin intermediate filament network in the cancer cell adhesion machinery.
PPFIA1 is located at the 11q13 region, which is one of the most commonly amplified regions in several epithelial cancers including head and neck squamous cell carcinoma and breast carcinoma. Considering the location of PPFIA1 in this amplicon, we examined whether protein encoded by PPFIA1, liprin-α1, possesses oncogenic properties in relevant carcinoma cell lines. Our results indicate that lipr...
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ژورنال
عنوان ژورنال: Cell Communication and Signaling
سال: 2018
ISSN: 1478-811X
DOI: 10.1186/s12964-018-0253-y